The postoperative hepatic dysfunction has wide clinical spectrum, from mild abnormality on liver function test without clinical symptom to life-threatening hepatic failure following operative procedure under general anesthesia.
To identify the contributing factors and susceptible patients to this hepatic dysfunction, we carried out a prospective study on 120 patients who underwent various types of surgery at the Department of Surgery, National Police Hospital, from
April
1993
through March 1994.
@ES the results were as follows:
@EN 1) The incidence of hepatic dysfunction was 14.2% (17 among 120 patients).
2) the most prevalent age group were sixth and seventh decades, and the male to female incidence ratio was 2:1.
3) The incidence was 15.1% in emergeny operation, and 14.6% in elective operation (P>0.05).
4) The incidence in malignant diseases was 18.9%, and 12.0% in benign diseases (P>0.05).
5) The incidence of postoperative hepatic dysfunction was significantly higher in patients who underwent operations on gallbladder. Stomah and spleen (P<0.005).
6) Opeation time had no significant effect ofn the incidence of postoperative hepatic dysfunction.
7) The incidence of postoperative hepatic dysfunction in transfused patients was 22.2%, and 12.7% in patients without transfusion.
8) The hepatic dysfunctions were all manifested within 2 weeks after operations, with average 4.7 days.
9) All patients with hepatic dysfunction recovered completely within 5 weeks, with average 9.3 days.
10) There was no death due to hepatic dysfunction.
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